Tumour iSAWE 17

Question

A 16 year old boy has a hard lump behind his knee that hurts when he kneels.

Tumour iSAWE 17, lateral radiograph of the knee
Lateral radiograph of the knee. Image by Michael R Carmont, Sian Davies, Daniel Gey van Pittius and Robin Rees, Wikimedia Commons, CC BY 2.0.
  1. Describe the radiograph and the pathology.
  2. What symptoms or signs would suggest malignant change?
  3. When would you excise it and how?

Answer

Radiograph

  • Pedunculated bony projection from the posterior distal femoral metaphysis
  • Cortex and medulla continuous with the host bone
  • Points away from the joint
  • Solitary osteochondroma (exostosis)

Pathology

  • Most common benign bone tumour
  • Displaced physeal cartilage grows at an angle to the physis
  • EXT1 or EXT2 mutations in hereditary multiple exostoses
  • Growth stops at skeletal maturity

Malignant change

  • Under 1% for solitary lesions, higher in multiple exostoses
  • New pain or growth after skeletal maturity
  • Cartilage cap over 2 cm in adults on MRI
  • Irregular or destroyed lesion margin, soft tissue mass
  • Secondary peripheral chondrosarcoma

Excision

  • Pain, mechanical symptoms, nerve or vessel compression, bursitis, cosmesis or concern for malignancy
  • Excise the whole cartilage cap and perichondrium to prevent recurrence
  • Delay until near maturity if possible
  • Popliteal vessels and nerves at risk in this location

Related pages

Author Contributions

Orthofracs team

Reviewed by Professor Phong Tran, Head of Orthopaedic Surgery, Western Health. Last updated 10 October 2026.