| Bacterial Group | Toxin | Treatment |
|---|---|---|
| Staphylococci | ||
| G + cocci in clusters S aureus S epidermidis | Exotoxins proteolytic haemolytic pyogenic enterotoxin | Flucloxacillin (Vancomycin) |
| Streptococci | ||
| G + cocci in chains Beta-haemolytic Group A S pyogenes Group B S agalactinae Group G S faecalis Enterococcus Non beta-haemolytic S pneumoniae S viridans | Exotoxins haemolysins hyaluronidase streptokinase | Penicillin |
| G – Enteric Bacteria | ||
| G – bacilli | ||
| Heterogenous group E coli Klebsiella Proteus Enterobacter Serratia Shigella Vibrio cholera | Endotoxin fever hypotension inflammation Exotoxin diarrhoea | Various sensitivities Gentamicin covers most (3rd generation cephalosporin) |
| Pseudomonas | Ceftazidime Ticarcillin Ciprofloxacin | |
| Haemophilus | ||
| G – bacillus H influenzae | Augmentin (Cefotaxime) | |
| Neisseria | ||
| G – diplococcus N meningitidis N gonorrhoea | Penicillin (Tetracycline) | |
| Necrotising Fasciitis | ||
| Group A strep (S pyogenes) Other aerobes/ anaerobes common | Debride Empiric triple AB | |
| Gas Gangrene | ||
| G + bacillus Clostridium perfringens (welchii) (proteolytic or saprophytic) | Exotoxin | Debride Penicillin (Metronidazole) |
| Tetanus | ||
| G + bacillus Prevent by TT/ TIG Clostridium tetani (tetanospasmin, tetanolysin) | Exotoxin | Debride Penicillin |
| Tuberculosis | ||
| AFB Mycobacterium tuberculosis | Isoniazid +Rifampicin | |
| Leprosy | ||
| AFB Mycobacterium leprae | Sulphones + Rifampicin Prednisone for acute neuro loss Treatment Charcot joints | |
| Syphilis | ||
| Spirochaete Treponema pallidum | Penicillin |
