Charcot Arthropathy

Western Health Orthopaedic Registrar presentation
Dr Daniel Sydenham

Charcot Arthropathy, radiograph of charcot arthropathy of the foot
Radiograph of Charcot arthropathy of the foot. Image by Hellerhoff, Wikimedia Commons, CC BY-SA 3.0.

Epidemiology

  • Usually develops in weight bearing joints
  • Usually secondary to DM in lower extremity & syringomyelia in shoulder
  • Associated with peripheral neuropathy

Pathology

Pathogenesis

  • Usually develops in weight bearing joints
  • Usually secondary to
    • diabetes mellitus in lower extremity
    • syringomyelia in shoulder
  • Associated with peripheral neuropathy

Histology

  • osteochondral fragments embedded within synovium
  • Related to destruction of afferent proprioceptive fibres & subsequent unrecognized trauma to joint

Classification

Staging (Eichenholtz)

StageDescription
0diabetic patient with peripheral neuropathy & acute ankle sprain or Fracture
1Fragmentationacute inflammatory process characterised by oedema, hyperaemia & erythema & bony fragmentation on X-rays
2Coalescenceswelling, redness & warmth with coalescing new bone at site of fracture or dislocation on X-rays
3Resolutionresolution of clinical inflammation & bony consolidation on X-ray (usu 9-12 mos after onset)

Treatment

StageTreatment
0always treat acute ankle fractures immediately
ORIF has ↑ complications including wound necrosis & amputation
if casting, must remain NWB > 6 weeks
treat ankle sprains aggressively with NWB & foam walker boot
1Fragmentationhigh rate of complications following surgery
NWB in total contact casts or foam walker boot for prolonged periods of time (up to 9-12 mos) until reparative stage reached
2Coalescenceas above
3Resolutioncan intervene surgically at this stage but still has ↑ risk of complications
usually performing reconstructive fusions to prevent pressure points & recurrent ulceration

Preoperative Evaluation

  • internal medicine consult
    • control of diabetes
    • assessment of end organ dysfunction
  • vascular consult
    • assess vascular supply to foot
  • document neuropathy
    • vibration sense & filament tests

Indications for Surgery

  • R ecurrent ulceration
  • I nfection
  • P ain

Reviewed by Professor Phong Tran, Head of Orthopaedic Surgery, Western Health. Last updated 10 October 2026.