Biomechanics of fracture healing & fracture stability

Definitions

  • Strain is change in fracture gap length divided by original gap length
  • Stiffness is resistance to deformation under load
  • Interfragmentary strain tolerance is about 100% for granulation tissue, 10% for cartilage and 2% for bone

Stability and Healing

StabilityStrainHealingConstructs
AbsoluteUnder 2%Primary, no callusLag screw, compression plate, tension band
Relative2 to 10%Secondary, with callusIntramedullary nail, bridge plate, external fixator, cast
  • Strain over 10% prevents bone formation (Perren)
  • Comminution spreads strain across many gaps, so relative stability suits it

Construct Factors

  • Longer plate working length lowers stiffness and spreads strain
  • Leaving screw holes empty near the fracture increases working length
  • Larger nail diameter increases stiffness
  • External fixator stiffness rises with larger pin diameter, more pins, wider pin spread, bar closer to bone and added planes
  • Pin bending stiffness rises with the fourth power of radius
  • Locking plates act as internal fixators and do not rely on friction between plate and bone
  • Far cortical locking and dynamic locking screws reduce stiffness near the plate

Load Sharing

Clinical Relevance

  • Simple fracture patterns fixed with bridging constructs can develop high strain and nonunion
  • Over stiff locking constructs can cause asymmetric callus and delayed union

Reviewed by Professor Phong Tran, Head of Orthopaedic Surgery, Western Health. Last updated 10 October 2026.