Question
A 66 year old man with ankylosing spondylitis has a stiff hip 6 months after total hip replacement.

- How is this classified?
- What are the risk factors and prophylaxis options?
- How is established disease managed?
Answer
Brooker classification
| Grade | Description |
|---|---|
| I | Islands of bone in the soft tissues |
| II | Spurs with at least 1 cm between opposing surfaces |
| III | Spurs with less than 1 cm between surfaces |
| IV | Apparent bony ankylosis |
Risk factors
- Previous heterotopic ossification
- Male sex, ankylosing spondylitis, DISH and hypertrophic osteoarthritis
- Paget disease and head injury
- Extensive soft tissue dissection
Prophylaxis
- NSAIDs such as indomethacin for several weeks
- Single dose radiotherapy within 24 hours before or 72 hours after surgery
- Avoid NSAIDs with renal impairment or when bone healing is needed
Established disease
- Excision for functional limitation in Brooker III and IV
- Wait for maturation, usually 6 to 12 months
- Prophylaxis after excision to prevent recurrence
Related pages
Author Contributions
Orthofracs team
Reviewed by Professor Phong Tran, Head of Orthopaedic Surgery, Western Health. Last updated 10 October 2026.