Intersection Syndrome

Definition

Tenosynovitis where the first dorsal compartment muscle bellies (APL and EPB) cross the second compartment tendons (ECRL and ECRB) in the distal forearm.

Aetiology

  • Repetitive wrist flexion and extension
  • Rowers, canoeists, weightlifters and skiers

Epidemiology

Pathology

  • Stenosing tenosynovitis of the second dorsal compartment sheath
  • Friction where APL and EPB cross the radial wrist extensors
  • Crossing point 4 to 8 cm proximal to Lister’s tubercle

Clinical Features

  • Pain and swelling over the dorsoradial distal forearm
  • Palpable or audible crepitus, the squeaker’s wrist
  • Tenderness proximal to the first dorsal compartment
  • Finkelstein test may be mildly positive
  • Pain on resisted wrist extension and thumb abduction
  • Fusiform swelling may be visible in thin patients

Investigations

  • Clinical diagnosis
  • Ultrasound or MRI shows peritendinous oedema at the crossing point
  • Radiographs normal, used to exclude fracture or arthritis

Differential Diagnosis

Management

  • Activity modification. Avoid the provoking wrist motion
  • Splinting. Wrist in slight extension for 2 to 3 weeks
  • NSAIDs. Symptom relief alongside rest
  • Corticosteroid injection. Into the second compartment sheath at the crossing point
  • Surgical release. Second dorsal compartment release and debridement for refractory symptoms

Prognosis

  • Most settle with rest and splinting
  • Recognition avoids an unnecessary first compartment release

References

  1. Grundberg AB, Reagan DS. Pathologic anatomy of the forearm. Intersection syndrome. J Hand Surg Am. 1985, 10(2), 299-302. PubMed
  2. Hanlon DP, Luellen JR. Intersection syndrome. A case report and review of the literature. J Emerg Med. 1999, 17(6), 969-71. PubMed

Reviewed by Professor Phong Tran, Head of Orthopaedic Surgery, Western Health. Last updated 19 October 2026.