Metabolic & Endocrine Disorders in Orthopaedics
Rickets & Osteomalacia
Definition
- Deficiency of calcium and/ or phosphate which results in inadequate osteoid mineralization
- Less mineralized bone per volume of bone
- Increased uncalcified osteoid
- Rickets - immature skeleton
- Osteomalacia - mature skeleton
- Bone formation is slowed & unmineralized osteoid accumulates along new bone surfaces
- Osteoid is the organic component of woven bone & can be mineralized or unmineralized
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