Factors affecting fracture healing

Blood Supply
- Soft tissue injury
- Radiation
- Chemical or thermal burns
- Infection
- Anaemia & hypoxia
- Denervation
- Excessive compression (more than 30lbs)
- Age
2. Excessive Movement
- Inadequate immobilisation
- Inadequate fixation or compliance
3. Gap
- Intact fellow bone
- Interposed soft tissue
- Distraction of bones
4. Other
- Nutrition (Vit C required for normal collagen)
- Drugs (corticosteriods inhibit osteoblast differentiation